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· They are highly resistance environmental stress such as temperature, irradiation, strong acids, disinfection -----etc. Endospores are formed by vegetative cells in response to environmental signals that indicate a limiting factor for vegetative growth, such as exhaustion of an essential nutrient. They germinate and become vegetative cells when the environmental stress is relieved. By forming spores, bacteria can survive in hostile conditions. Spores are resistant to heat, dessication, chemicals, and radiation.

Vegetative bacterial cells

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This indirect method is called Tyndallization. It was the usual method for a while in the late 19 th century before the advent of inexpensive autoclaves. Inactivation of Bacterial Spores and Vegetative Bacterial Cells by Interaction with ZnO-Fe2O3 Nanoparticles and UV Radiation[J]. AIMS Geosciences, 2017, 3(4): 498-513. doi: 10.3934/geosci.2017.4.498 José Luis Sánchez-Salas, Alejandra Aguilar Ubeda, Beatriz Flores Gómez, Oscar Daniel Máynez Navarro, Miguel Ángel Méndez Rojas, Silvia Reyna Tellez, Erick R. Bandala.

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· They are resistance to ultra violet radiation high temperature, extreme freezing and chemical disinfectants · They are highly resistance environmental stress such as temperature, irradiation, strong acids, disinfection -----etc. Although cryptobiotic, they retain viability indefinitely such that under appropriate environmental conditions, they germinate back into vegetative cells. Endospores are formed by vegetative cells in response to environmental signals that indicate a limiting factor for vegetative growth, such as exhaustion of an essential nutrient. While the vegetative cell is the active form for bacterial cells (growing, metabolizing, etc), the endospore can be thought of as a dormant form of the cell.

Vegetative bacterial cells

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Vegetative bacterial cells

Vegetative Cells vs Endospores of Bacteria (Difference between Vegetative Cells and Endospores of Bacteria) Bacterial endospores are special tough, dormant and resistant spores produced by some Gram-positive bacteria of during unfavorable environmental conditions. They help the bacteria to endure the unfavorable conditions. They are any bacterial cells (both harmless and harmful) that are multiplying, feeding, excreting, and doing all the things that active bacteria normally do.

There are even some bacteria which grow in deep ocean volcanic vents that can only live and grow at very high pressures and boiling (212oF or 100oC or greater) temperatures. The vegetative cells of most bacteria, including food pathogens, spoilage bacteria, and the Define vegetative cell. vegetative cell synonyms, vegetative cell pronunciation, vegetative cell translation, English dictionary definition of vegetative cell Once the bacterial cell initiates sporulation, the process begins with the termination of vegetative cell growth and the formation of an axial filament, an elongated nucleotide structure that extends to the length of the cell (Stage 0). The cell which produces spores and which is metabolically active is known as a vegetative cell. Vegetative cell grows rather than producing spores. It contains a high amount of water content, and it is not resistant to harsh environmental conditions.
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By forming spores, bacteria can survive in hostile conditions. Spores are resistant to heat, dessication, chemicals, and radiation.

Vegetative cell grows rather than producing spores. It contains a high amount of water content, and it is not resistant to harsh environmental conditions.
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vegetative bacteria - Swedish translation – Linguee

  • A bacterium produces a single endospore, which merely helps the survival not reproduction. Include most bacterial vegetative cells, most fungal spores and hyphae, yeasts, envelope viruses, and protozoan trophozoites.


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Unlike spores, vegetative cells are susceptible to disinfectants, heat, chemicals, radiation, etc. cell structure.